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NODAL
PDBに登録されている構造 PDB オルソログ検索: RCSB PDBe PDBj PDBのIDコード一覧 4N1D
識別子
記号	NODAL, HTX5, nodal growth differentiation factor
外部ID	OMIM: 601265 MGI: 97359 HomoloGene: 8417 GeneCards: NODAL
遺伝子の位置 (ヒト) 染色体 10番染色体 (ヒト) バンド データ無し 開始点 70,431,936 bp 終点 70,447,951 bp
遺伝子の位置 (マウス) 染色体 10番染色体 (マウス) バンド データ無し 開始点 61,253,751 bp 終点 61,261,117 bp
遺伝子オントロジー 分子機能 • 受容体リガンド活性 • cytokine activity • type I activin receptor binding • morphogen activity • transforming growth factor beta receptor binding • growth factor activity 細胞の構成要素 • 細胞外領域 • 細胞外空間 生物学的プロセス • trophectodermal cellular morphogenesis • left lung morphogenesis • nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry • neural fold formation • maternal process involved in parturition • cell fate commitment • 内胚葉の発生 • transforming growth factor beta receptor signaling pathway involved in primitive streak formation • floor plate morphogenesis • endodermal cell differentiation • epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification • SMAD protein signal transduction • embryonic pattern specification • polarity specification of proximal/distal axis • positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry • 消化器系発生 • positive regulation of cell-cell adhesion • 肺発生 • positive regulation of epithelial cell proliferation • 胎座 • negative regulation of cell differentiation • positive regulation of pathway-restricted SMAD protein phosphorylation • mesoderm formation • negative regulation of androgen receptor signaling pathway • gastrulation with mouth forming second • anatomical structure formation involved in morphogenesis • positive regulation of DNA-binding transcription factor activity • regulation of stem cell population maintenance • formation of anatomical boundary • embryonic placenta development • in utero embryonic development • negative regulation of transcription by RNA polymerase II • negative regulation of trophoblast cell migration • 組織の形態形成 • BMP signaling pathway • 神経系発生 • positive regulation of angiogenesis • embryonic heart tube development • nodal signaling pathway • stem cell population maintenance • 多細胞個体の発生 • heart looping • embryonic process involved in female pregnancy • 心臓発生 • positive regulation of cysteine-type endopeptidase activity involved in apoptotic process • 脳発生 • axial mesodermal cell fate specification • 脈管構造発生 • positive regulation of activin receptor signaling pathway • determination of left/right symmetry • maternal placenta development • regulation of signal transduction • 原腸形成 • trophectodermal cell differentiation • mesendoderm development • positive regulation of cell population proliferation • positive regulation of ERK1 and ERK2 cascade • embryonic cranial skeleton morphogenesis • 肝臓発生 • positive regulation of vascular endothelial growth factor production • cell migration involved in gastrulation • negative regulation of chorionic trophoblast cell proliferation • anterior/posterior axis specification • 遊走 • regulation of gastrulation • primitive streak formation • negative regulation of cell development • positive regulation of transcription by RNA polymerase II • digestive tract morphogenesis • positive regulation of SMAD protein signal transduction • anterior/posterior pattern specification • inhibition of neuroepithelial cell differentiation • 細胞発生 • regulation of signaling receptor activity • regulation of apoptotic process • regulation of MAPK cascade • シグナル伝達 出典:Amigo / QuickGO
オルソログ
種	ヒト	マウス
Entrez	4838	18119
Ensembl	ENSG00000156574	ENSMUSG00000037171
UniProt	Q96S42,H7C0E4	P43021
RefSeq (mRNA)	NM_018055 NM_001329906	NM_013611
RefSeq (タンパク質)	NP_001316835 NP_060525	NP_038639
場所 (UCSC)	Chr 10: 70.43 – 70.45 Mb	Chr 10: 61.25 – 61.26 Mb
PubMed検索
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